Retin-A Tretinoin 0.05% Cream 20g made by Jannsen Cilag, Johnson & Johnson – is created to treat acne, also flawlessly used to reduce and gradually remove the appearance of wrinkles & age spots, the roughness of facial skin while also facilitating the disappearance of darker and lighter spots. Tretinoin Cream must be used with a total skin care and sunlight avoidance program. It is one of a family of gels called Retinoids, and is effective in preventing pimples and healing existing pimples. It can also be used to reduce the signs of ageing like facial lines and sun spots, as well as alone or with other topical treatments to treat alopecia and other kinds of hair loss. Use always with medicated SPF filters lotions and creams. Using of quality moisturizers are also necessary.